چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | علوم پزشکی کرمانشاه |
| نویسنده | نفر چندم مقاله |
|---|---|
| وهاب دهلقی | اول |
| عنوان | متن |
|---|---|
| کلمات کلیدی | INVESTIGATION OF WALL SHEAR STRESS DISTRIBUTION IN STENTED CORONARY ARTERY BIFURCATION V. Dehlaghi1, S. Najarian2, A. Rai1 1Kermanshah University of Medical Sciences, Kermanshah, Iran, 2Amirkabir University of Technology, Tehran, Tehran, Iran Background: Alteration of arterial wall shear stress (WSS) may cause endothelial damage which is believed to be a major cause of plaque and thrombus formation. Stent implantation affects WSS values which might lead to in-stent restenosis, and plaque formation in pre-stent and post-stent regions. In this study, an investigation on the effects of stent geometry and bifurcation angle on blood flow pattern in a stented coronary artery is reported. Methods: Stents are assumed with real structure and modeled using the commercial software package (Gambit, V2.0). Blood flow was assumed as pulsatile, incompressible, and Newtonian flow. Rigid boundary conditions were assumed for all models. The governing Navier-Stokes equations were solved using commercial software package (Fluent V6.0.12). Wall shear stress distribution was computed in three different sites, pre-stent, stented arterial segment, and post-stent regions using computational fluid dynamics. Results: It is concluded that shear stress is influenced by stent design parameters, i.e., strut spacing, strut profile, and number of struts and bifurcation angle. To achieve the most secure shear stress value, the optimum stent geometry can be obtained with respect to the mentioned parameters for a specific arterial segment. Different stents may be used for different arteries and arterial branches due to the dependency of the shear stress value to the geometry of the artery. It is shown that analyses of wall shear stress profile in stented segment, pre-stent and post-stent regions are essential in stent design. Conclusions: Mechanical parameters which might contribute to restenosis are highly sensitive to stent geometry, length, and bifurcation angle. |
| چکیده | |
| متن مقاله | |
| نتیجه مقاله |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| عکس دکتر وهاب دهلقی.jpg | دانلود |
