چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | علوم پزشکی کرمانشاه |
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| کلمات کلیدی | Effect of Zinc supplementation on respiratory infections in children with cystic fibrosis Khorasani N E ,Mansouri F. Respiratory ward , Kermanshah University of Medical science, Iran. Introduction:Zinc has significant anti-oxidant and anti-inflammatory activity.Zn deficiency can occur in subsets of patients with cystic fibrosis(CF) especially those with malabsorption .Although Zn has significantly reduced infections in various disorders,But its efficacy has not been thoroughly investigated in CF. Methods:We performed a double blind placebo controlled study to investigat the effect of daily 5mg/Kg(Max 30mg)elemental Zn for one year on rate of respiratory tract infection in20 children with CF(ages 7-18). Plasma Zn,pulmonary function tests(PFT),Rate of respiratory infections and use of antibiotics measured at baselineand end of the study. Results: Rate of respiratory infections and use of antibiotics was lower in Zn treated compared to plasbo(P<0.05). Conclusion:Oral Zn supplementation(5mg/Kg)reduce the rate of respiratory infections and antibiotic usaged in children with CF. Key Word:Cystic fibrosis,Zinc,Respiratory Infection ,antibiotic . |
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