چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | علوم پزشکی کرمانشاه |
| کد مقاله | 7887 |
| عنوان فارسی مقاله | |
| عنوان لاتین مقاله | Anti-tuberculosis drug resistance in west of IRAN |
| نوع ارائه | پوستر |
| عنوان کنگره / همایش | هشتمین کنگره بین المللی آزمایشگاه و بالین و اولین کنگره ملی علوم پایه پزشکی و تولید دانش بنیان |
| نوع کنگره / همایش | بین المللی |
| کشور محل برگزاری کنگره/ همایش | ایران |
| شهر محل برگزاری کنگره/ همایش | تهران |
| سال انتشار/ ارائه شمسی | 1394 |
| سال انتشار/ارائه میلادی | 2016 |
| تاریخ شمسی شروع و خاتمه کنگره/همایش | 1394/11/17 الی 1394/11/19 |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | http://isaclcongress.ir/Default.aspx |
| آدرس علمی (Affiliation) نویسنده متقاضی | 2.0000 |
| نویسنده | نفر چندم مقاله |
|---|---|
| پرویز مهاجری | اول |
| بهارک نوروزی | دوم |
| عنوان | متن |
|---|---|
| کلمات کلیدی | Mycobacterium tuberculosis, Drug Resistant |
| چکیده | Background and Aim: Mycobacterium tuberculosis has developed resistance to anti-tuberculosis drugs and becoming a major and alarming public health problem in worldwide. This study aimed to determine antituberculosis drug resistance rate and to identify multidrug resistant tuberculosis (MDR-TB) in west of Iran. Methods: Total of 130 samples was included Between Decembers 2011 and July 2012 in the study from that 112 cases were Mycobacterium tuberculosis. The proportional method was carried out according to the CLSI on Lowenstein-Jensen against isoniazid, rifampicin, streptomycin, ethambutol, pyrazinamide, para aminosalsilic acid, etionamid, cyclocerine. The microdillution method was carried out using 7H9 broth with 96 well-plates. Results: From 112 isolates, resistance was observed to isoniazid 18 (16.07%), rifampicin 16 (14.28%), streptomycin 25 (22.32%), ethambutol 15 (13.39%), pyrazinamide 27 (24.10%), para aminosalicylic acid 19 (16.96%), cycloserine 4 (3.57%) and ethionamid 14 (12.5%) cases. 16 isolates were multidrug-resistant. Conclusion: The high prevalence of MDR-TB in our study is assumed to be due to recent transmission of drug resistant strains. Overall, the rate of drug resistance in our study was high, which is in line with findings of some high-burden countries. So that early case detection, rapid drug susceptibility testing, effective anti-TB treatment is necessary. |
| متن مقاله | Background and Aim: Mycobacterium tuberculosis has developed resistance to anti-tuberculosis drugs and becoming a major and alarming public health problem in worldwide. This study aimed to determine antituberculosis drug resistance rate and to identify multidrug resistant tuberculosis (MDR-TB) in west of Iran. Methods: Total of 130 samples was included Between Decembers 2011 and July 2012 in the study from that 112 cases were Mycobacterium tuberculosis. The proportional method was carried out according to the CLSI on Lowenstein-Jensen against isoniazid, rifampicin, streptomycin, ethambutol, pyrazinamide, para aminosalsilic acid, etionamid, cyclocerine. The microdillution method was carried out using 7H9 broth with 96 well-plates. Results: From 112 isolates, resistance was observed to isoniazid 18 (16.07%), rifampicin 16 (14.28%), streptomycin 25 (22.32%), ethambutol 15 (13.39%), pyrazinamide 27 (24.10%), para aminosalicylic acid 19 (16.96%), cycloserine 4 (3.57%) and ethionamid 14 (12.5%) cases. 16 isolates were multidrug-resistant. Conclusion: The high prevalence of MDR-TB in our study is assumed to be due to recent transmission of drug resistant strains. Overall, the rate of drug resistance in our study was high, which is in line with findings of some high-burden countries. So that early case detection, rapid drug susceptibility testing, effective anti-TB treatment is necessary. |
| نتیجه مقاله | From 112 isolates, resistance was observed to isoniazid 18 (16.07%), rifampicin 16 (14.28%), streptomycin 25 (22.32%), ethambutol 15 (13.39%), pyrazinamide 27 (24.10%), para aminosalicylic acid 19 (16.96%), cycloserine 4 (3.57%) and ethionamid 14 (12.5%) cases. 16 isolates were multidrug-resistant |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| Bacteriology-poster.pdf | 1394/11/25 | 1775323 | دانلود |
| request-2 001.jpg | 1394/11/25 | 484098 | دانلود |
| Congress 001.jpg | 1394/11/25 | 1161662 | دانلود |
