| چکیده | Isolation and antibiotic susceptibility of Salmonella typhi from stool samples among hospitalized patients in Kermanshah ,West Iran(2012-2015) BaharehZalei1,ZhaleDezfoolimanesh2, Farshid Raessi3, Hayas Fatahi4 1- Departent of medical laboratory sciences ,Emam Ali hospital , Kermanshah university of medimcal sciences, Kermanshah,Iran 2-Departent of medical laboratory sciences ,paramedicineschool , Kermanshah university of medimcal sciences, , Kermanshah,Iran 3-Depertent of pathology sciences, Emam Ali hospital , Kermanshah university of medimcal sciences, Kermanshah,Iran 4- Departent of medical laboratory sciences ,Emam Reza hospital , Kermanshah university of medimcal sciences, , Kermanshah,Iran Introduction: Typhoid fever (enteric fever) caused by the bacteriumSalmonella enteric and is often contracted by ingestion of food or water that is contaminated with the pathogen usually from a feco-oral source.The aim of this study wasisolation and antibiotic susceptibility of Salmonella typhi from stool samples among hospitalized patients in Kermanshah ,West Iran. Methods: This prospective cross sectional study was conducted in a teaching hospital in Kermanshah, Iran during April 2012 to March2015.Patients with systematic infection were selected for this study.Stool specimens were collected from patients. All isolates were confirmed as Salmonellatyphi by biochemical and serologic tests. Antibiotic sensitivity pattern of these isolates was studied by disk diffusion Method.The routinely used antibiotics wereChloramphenicol ,Cephalexin,Ciprofloxacin,Gentamycin,Cefixime,Nitrofurantoin,Nalidixicacid,Ceftriaxone,Ampicillin,Cotrimoxazole,Imepenem,Cefotaxime and Amikacin.Spss15used for analysis. Results :Fourty (3/3%) samples out of the total 1232 were positive for bacterial growth. The organisms isolated include Salmonella typhi; 10 (0/8%),Enterobacter; 16 (1/3%)andCitrobacter; 14 (1/1%).Salmonella typhi was mostly sensitive againstImepenem(75%),Cefixime(55%), Gentamycin(45%)and chloramphenicol (30%).100% isolated were resistant toCeftriaxone,Cefotaximeand ciprofloxacin. Conclusions:The emergence of antimicrobial resistance, especially the multidrug resistance to ampicillin, chloramphenicol, and cotrimoxazole, has further complicated the treatment and management of enteric fever. Keywords:Salmonellatyphi, Susceptibility, Antibiotic,: Kermanshah |