چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | علوم پزشکی کرمانشاه |
| کد مقاله | 9226 |
| عنوان فارسی مقاله | |
| عنوان لاتین مقاله | Effect of selenium supplementation on lipid profile in hemodialysis patients |
| نوع مقاله | مقاله اصیل (پژوهشی، Original) |
| بالاترین نمایه نامه بینالمللی | pubmed |
| سطح مقاله | |
| IF | |
| عنوان نشریه | J Renal Inj Prev |
| نوع نشریه | داخلی ایندکس شده |
| شماره نشریه | 4 |
| دوره | 5 |
| تاریخ انتشار شمسی | 1395/07/10 |
| تاریخ انتشار میلادی | |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | http://journalrip.com/Archive/5/4 |
| DOI | 10.15171/jrip.2016.38 |
| آدرس علمی (Affiliation) نویسنده متقاضی | Nephrology and Urology Research Center,Kermanshah University Of Medical Sciences,Kermanshah,Iran |
| Introduction: One of the major causes of mortality in chronic kidney disease (CKD) patients on hemodialysis is premature atherosclerosis. Selenium, a trace element involved in important enzymatic activities inside the body, has protective effects against lipid oxidation and inhibits cholesterol accumulation in blood vessels. Objectives: To determine the effect of selenium supplementation on lipid profile in hemodialysis patients. Patients and Methods: In this double-blinded randomized clinical trial which lasted for 3 months, 84 hemodialysis patients with selenium deficiency were divided into experimental group (received selenium supplementation) or control group (received placebo). Total cholesterol, low-density lipoprotein (LDL-C), high-density lipoprotein (HDL-C), blood urea nitrogen (BUN), creatinine, and selenium level were measured before and after the study. Results: Mean (±SD) serum LDL-C level significantly increased in experimental group from 85.66 (±31.12) to 109.12 (±32.29) mg/dl (P < 0.001). Likewise, in control group serum LDL-C significantly increased from 80.55 (±21.13) to 97.05 (±28.07) mg/dl (P < 0.001). However, with control of LDL-C effect before and after the study, it was revealed that LDL-C change was not statistically significant (P = 0.21). Similarly, total cholesterol and triglyceride levels did not show significant changes before and after the study in any group. Conclusion: Selenium supplementation had no beneficial effect on lipid profile in hemodialysis patients |
| نویسنده | نفر چندم مقاله | نویسنده مسئول |
|---|---|---|
| یحیی پاسدارخشکناب | سوم | خير |
| افشین الماسی | پنجم | خير |
| کامبیز جاسمی | چهارم | خير |
| حمیدرضا عمرانی | اول | خير |
| سیما گل محمدی | دوم | بلي |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| JRIP-5-179.pdf | 1395/08/08 | 376876 | دانلود |
