چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | علوم پزشکی کرمانشاه |
| کد مقاله | 9227 |
| عنوان فارسی مقاله | |
| عنوان لاتین مقاله | The effect of selenium supplementation on acute phase reactants and thyroid function tests in hemodialysis patients |
| نوع مقاله | مقاله اصیل (پژوهشی، Original) |
| بالاترین نمایه نامه بینالمللی | pubmed |
| سطح مقاله | |
| IF | |
| عنوان نشریه | nephro-urology monthly |
| نوع نشریه | داخلی ایندکس شده |
| شماره نشریه | 2 |
| دوره | 7 |
| تاریخ انتشار شمسی | 1393/12/11 |
| تاریخ انتشار میلادی | |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | http://numonthly.com/ |
| DOI | 10.5812/numonthly.24781 |
| آدرس علمی (Affiliation) نویسنده متقاضی | Nephrology and urology Research Center,kermanshah University of medical sciences,Kermanshah,Iran |
| Background: Selenium deficiency is a common problem in patients with chronic kidney disease (CKD). This micronutrient has antiinflammatory and anti-oxidant effects. Selenium is also found in high concentrations in the thyroid gland. Objectives: To determine the effect of selenium supplementation on thyroid function tests and acute phase reactants in hemodialysis patients. Patients and Methods: In this double-blinded randomized clinical in 3 months, 64 hemodialysis patients with selenium deficiency were divided into experimental (received selenium supplementation; 32 cases) or control group (received placebo; 32 cases). Erythrocyte sedimentation rate (ESR), ferritin, quantitative C-reactive protein (CRP) and thyroid function tests (TFTs) including thyroid stimulating hormone (TSH), T3 resin uptake (T3RU), and free T4 were measured before and after the intervention and compared between experimental and control groups. Results: At baseline, no significant difference was found between experimental and control groups regarding CRP, ESR and ferritin serum levels. Likewise, after intervention, no significant difference was found between experimental and control groups for CRP (14.77 ± 17.93 vs. 18.29 ± 21.56 mg/L), ESR (32.90 ± 32.62 vs. 33.91 ± 31.15 mm/h) and ferritin (528.6 ± 423.07 vs. 519.52 ± 345.59 ng/mL). At baseline, no significant difference was found between experimental and control groups regarding TFTs. Likewise, after intervention, no significant difference was found between experimental and control groups for TSH (3.7 ± 2.22 vs. 2.84 ± 1.88 µU/mL), free T4 (7.19 ± 1.98 vs. 7.02 ± 1.87 µg/dL) and T3RU (30.04 ± 2.28% vs. 29.2 ± 1.98%). Conclusions: Oral selenium supplementation for three months did not have any significant effect on thyroid function tests or acute phase reactants. |
| نویسنده | نفر چندم مقاله | نویسنده مسئول |
|---|---|---|
| مهرعلی رحیمی | دوم | خير |
| حمیدرضا عمرانی | اول | بلي |
| کنعان نیک سرشت | سوم | خير |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| num-07-02-24781.pdf | 1395/08/08 | 69889 | دانلود |
