چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | علوم پزشکی کرمانشاه |
| کد مقاله | 9228 |
| عنوان فارسی مقاله | |
| عنوان لاتین مقاله | The effect of allopurinol treatment regimen on serum uric acid and arterial blood pressure in hemodialysis patients |
| نوع مقاله | مقاله اصیل (پژوهشی، Original) |
| بالاترین نمایه نامه بینالمللی | ISC |
| سطح مقاله | |
| IF | |
| عنوان نشریه | مجله دانشگاه علوم پزشکی کرمانشاه |
| نوع نشریه | داخلی ایندکس شده |
| شماره نشریه | 2 |
| دوره | 20 |
| تاریخ انتشار شمسی | 1395/04/11 |
| تاریخ انتشار میلادی | |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | http://journals.kums.ac.ir/ojs/index.php/jkums |
| DOI | |
| آدرس علمی (Affiliation) نویسنده متقاضی | Department of Internal Medicine, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran. |
| Introduction: Controlling and reducing serum uric acid levels may have beneficial effects on blood pressure control. The current study was carried out to assess the effects of allopurinol administration on serum uric acid and arterial blood pressure among the patients under hemodialysis. Methods: This double-blind clinical trial was conducted on 132 hemodialysis patients (two separate groups) suffering from hyperuricemia and hypertension at Imam Reza hospital, Kermanshah in 2014. The first group received a daily dose of 100 mg allopurinol and the second group, as control, received placebo. The demographic data, vital signs, paraclinical data and comorbidities of all patients were recorded in a checklist. Serum uric acid and blood pressure were measured at the end of the first, second and third months. The obtained data were analyzed by SPSS software using t-test, paired t-test and repeated measure t-test. Results: The results showed that allopurinol significantly reduced systolic and diastolic blood pressure and uric acid level in the patients with chronic renal dysfunction. This reduction was also reported to be significant between the patient and control groups at different times. Conclusion: Given the beneficial effect of allopurinol on the patients with chronic renal dysfunction, this drug can be used in this group of patients |
| نویسنده | نفر چندم مقاله | نویسنده مسئول |
|---|---|---|
| امیرحسین هاشمیان | چهارم | خير |
| داریوش رئیسی | سوم | خير |
| حمیدرضا عمرانی | اول | خير |
| سید محمد کاظم صادقی | دوم | بلي |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|
