چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | علوم پزشکی کرمانشاه |
| کد مقاله | 9548 |
| عنوان فارسی مقاله | |
| عنوان لاتین مقاله | Beijing strains of Mycobacterium tuberculosis in smear-positive tuberculosis patients in North-West and West of Iran |
| نوع مقاله | مقاله اصیل (پژوهشی، Original) |
| بالاترین نمایه نامه بینالمللی | pubmed |
| سطح مقاله | |
| IF | |
| عنوان نشریه | Advanced Biomedical Research |
| نوع نشریه | خارجی ایندکس شده |
| شماره نشریه | 181 |
| دوره | 5 |
| تاریخ انتشار شمسی | 1395/09/11 |
| تاریخ انتشار میلادی | |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | http://www.advbiores.net/article.asp?issn=2277-9175;year=2016;volume=5;issue=1;spage=181;epage=181;aulast=Sahebi |
| DOI | 10.4103/2277-9175.190982 |
| آدرس علمی (Affiliation) نویسنده متقاضی | Department of Microbiology, Faculty of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran |
| Background: Tuberculosis (TB) is the leading cause of morbidity and mortality among chronic infectious diseases. The goal of this cross-sectional study (2012–2014) was to examine the prevalence of Mycobacterium TB (MTB) Beijing strains in regions near the Iranian border and to identify any epidemiological links. Materials and Methods: To this end, MTB isolates were harvested, from 64 HIV-negative, pulmonary smear-positive TB patients from the Iranian border provinces of East Azerbaijan (North-West), Kurdistan (West), and Kermanshah (West) (2012–2014). Isolates were subjected to restriction fragment length polymorphism (RFLP) analysis, using the insertion sequence IS6110 as a probe (IS6110 RFLP), and drug susceptibility testing by the proportion method. We gathered demographic and clinical data using a questionnaire and reviewing patient records. Results were analyzed with Gel Compare II 6.6 and SPSS-18. Results: The mean age of the patients was 54.4 years and 46.9% were male. The prevalence of Beijing strains among the isolates was 9.4% (17.6% in the Western provinces and 0% in East Azerbaijan). There was a statistically significant relationship between the Beijing strains and drug resistance and also between these strains, and the recurrence of TB in patients that had previously received treatment (P = 0.02 and P = 0.04, respectively). Conclusions: Finally, the prevalence of Beijing strains in Western Iran was greater than expected. Our results therefore indicate that regional and cross-border tracing may be necessary to control spread of this organism. |
| نویسنده | نفر چندم مقاله | نویسنده مسئول |
|---|---|---|
| پرویز مهاجری | چهارم | خير |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| Saebi-2016-2.pdf | 1395/09/13 | 1118040 | دانلود |
