چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | علوم پزشکی کرمانشاه |
| کد مقاله | 11269 |
| عنوان فارسی مقاله | |
| عنوان لاتین مقاله | Registry of Unrelated Hematopoietic Stem Cell Donors in West Iran:A Population Based Cross-Sectional Study |
| نوع ارائه | پوستر |
| عنوان کنگره / همایش | The 22nd International Coverages of Asia-Pacific Blood and Marrow Transplantation |
| نوع کنگره / همایش | بین المللی |
| کشور محل برگزاری کنگره/ همایش | ایران |
| شهر محل برگزاری کنگره/ همایش | تهران |
| سال انتشار/ ارائه شمسی | 1396 |
| سال انتشار/ارائه میلادی | 2017 |
| تاریخ شمسی شروع و خاتمه کنگره/همایش | 1396/08/06 الی 1396/08/08 |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | http://Www.apbmt2017.org |
| آدرس علمی (Affiliation) نویسنده متقاضی | 9.0000 |
| نویسنده | نفر چندم مقاله |
|---|---|
| مهرداد پاینده | اول |
| یداله شکیبا | دوم |
| سکینه قربانی | سوم |
| مریم باباخانی | هشتم |
| سعید جعفری | ششم |
| علی قاسمی | چهارم |
| مینا امیری | هفتم |
| محسن مسگریان | نهم |
| سمیه امیری | پنجم |
| عنوان | متن |
|---|---|
| کلمات کلیدی | HLA-match; Iran; Registry; Stem cell transplant; Unrelated Donors. |
| چکیده | Hematopoietic Stem Cell Transplantation (HSCT) is a curative method for both health-threatening malignant and nonmalignant conditions such as lymphoma, leukemia, immunodeficiencies, congenital metabolic disorders, hemoglobinopathies, and myelodysplastic and myeloproliferative syndromes. Nowadays, Donation of hematopoietic stem cells by an unrelated donor may be the only opportunity for 70% of those in need of hematopoietic stem cell transplantation, although HSCT with a Human Leukocyte Antigens (HLA) _matched donor like sibling is the first choice. Hence, individual donor registries are established across the world to facilitate finding the best available donor. |
| متن مقاله | Purpose: We sought to find (HLA)-matched donor for all patients with different racial/ethnic characteristics and also assess social contribution rates in donation of Hematopoietic Stem Cells (HSCs) in Kermanshah, west of Iran 2016-2017. Design/methodology/approach: This population based cross-sectional study have been constructed to estimate social contribution rates in donation of HSCs among those attending Health Care Centers, hospital etc. and also using mobile teams, in west Iran (2016-2017). Participants were excluded from the study if had chronic disease and/or aged less than 18 years or more than 55 years and/or those who did not sign consent form to participate in the study. A validated questionnaire was used to gather data related to the objectives of study. Under safety medical strategies, peripheral blood samples were collected in EDTA tubes and kept at -18 º C. All of tubes were labeled with the people's name and identification number. All data analysis was performed using statistical package for social sciences (SPSS) statistical software (Version 23; IBM Corporation, Chicago, USA). The categorical variables were summarized as frequency and percentages and also normally distributed continuous variables were reported as means and standard deviations. Using Chi-square, the relationships between outcome variable and predicting variables were assessed. Findings: Over ally 3669 unrelated stem cell donors contributed in stem cell donation campaign. Participant's ages were (31.36±1010.40y) (µ±SD) and most (59.6%) were men. There was no difference in nationality and religious status among donors. Many (39.7%) had completed academic education and most of them (60.6%, 2224/3669) were employee or student (academic level). Educational status was significantly associated with contribution rates (P-value≤0.05). |
| نتیجه مقاله | Hematopoietic stem cell donors registries are structured based on positive and altruistic feelings to save patients. Furthermore, continued recruitment of unrelated hematopoietic stem cell donors can increase the probability of finding an HLA-matched donor; although majority of patients of all racial/ethnic population still leave without a match. In conclusion, social contribution rates could be improved by educating people and providing encouragement strategies. |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| 2.pdf | 1396/12/23 | 1147810 | دانلود |
| 2.pdf | 1396/11/30 | 269561 | دانلود |
| 445211605_59522.jpg | 1396/11/30 | 253355 | دانلود |
| 445211605_59522.jpg | 1396/11/30 | 253355 | دانلود |
