چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | علوم پزشکی کرمانشاه |
| کد مقاله | 11956 |
| عنوان فارسی مقاله | |
| عنوان لاتین مقاله | Antibacterial effect of tramadol against Staphylococcus aureus and Pseudomonas aeruginosa: an in vivo study |
| نوع مقاله | مقاله اصیل (پژوهشی، Original) |
| بالاترین نمایه نامه بینالمللی | pubmed |
| سطح مقاله | هیچکدام |
| IF | |
| عنوان نشریه | New Microbes and New Infections |
| نوع نشریه | خارجی ایندکس شده |
| شماره نشریه | |
| دوره | 24 |
| تاریخ انتشار شمسی | 1397/04/10 |
| تاریخ انتشار میلادی | |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | https://www.sciencedirect.com/science/article/pii/S2052297518300295 |
| DOI | |
| آدرس علمی (Affiliation) نویسنده متقاضی | Department of Microbiology, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran |
| Some important adverse effects of local and regional anaesthesia including injection-site infection, epidural abscess and meningitis, are usuallycaused by bacteria such as Staphylococcus aureus and Pseudomonas aeruginosa. These infections can even cause the patient’s death in severecases. In the present study, the antimicrobial activity of tramadol was investigated on S. aureus and P. aeruginosa in BALB/c-sensitive mice. Thisexperimental multigroup research study evaluated the effect of two different concentrations of injectable tramadol (12.5 and 25 mg/mL) onlocal infections caused by S. aureus and P. aeruginosa in BALB/c mice within 24 and 48 hours. The results showed that tramadol injection in thespecified doses did not have a significant impact on the diameter of lesions caused by local infections due to these organisms. However, thediameter of inflammation resulting from local infection with P. aeruginosa had statistically increased in the two doses after 48 hours (p 0.019).Subcutaneous injection of tramadol reduced the growth of S. aureus through enhancing phagocytes and tissue inflammation; however, it didnot help eliminate P. aeruginosa, and at a dose of 25 mg/mL it also increased the growth and spread of the bacteria. It seems that the observeddifference was due to the different characteristics of these two bacteria |
| نویسنده | نفر چندم مقاله | نویسنده مسئول |
|---|---|---|
| علی گرگین کرجی | چهارم | خير |
| پرویز مهاجری | پنجم | بلي |
| منصور رضایی | ششم | خير |
| فرشته جلالوندی | هفتم | خير |
| حسین فرزام | اول | خير |
| عباس فراهانی | دوم | خير |
| علی تفتیک | سوم | خير |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| Dr Farzam.pdf | 1397/02/25 | 166249 | دانلود |
