Antifungal effects of six herbal extracts against Aspergillus sp. and compared to amphotericin B and nystatin


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پژوهان
صفحه نخست سامانه
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چکیده مقاله
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علوم پزشکی کرمانشاه
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نویسندگان: احمد تاجه میری

کلمات کلیدی: Anti-fungal effects Medicinal plants Aspergillus

نشریه: International Journal of Advanced and Applied Sciences , 7 , 5 ,

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کد مقاله 12049
عنوان فارسی مقاله
عنوان لاتین مقاله Antifungal effects of six herbal extracts against Aspergillus sp. and compared to amphotericin B and nystatin
نوع مقاله مقاله اصیل (پژوهشی، Original)
بالاترین نمایه نامه بین‌المللی ISI
سطح مقاله هیچکدام
IF
عنوان نشریه International Journal of Advanced and Applied Sciences
نوع نشریه خارجی ایندکس شده
شماره نشریه 7
دوره 5
تاریخ انتشار شمسی 1397/04/02
تاریخ انتشار میلادی
آدرس لینک مقاله/ همایش در شبکه اینترنت http://science-gate.com/IJAAS/Articles/2018/2018-5-7/07%202018-5-7-pp.53-57.pdf
DOI
آدرس علمی (Affiliation) نویسنده متقاضی Nosocomial Infection Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran

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Aspergillus is a filamentous fungus of wide distribution having widespread species diversity. Among pathogenic species of Aspergillus, Aspergillus fumigatus, Aspergillus niger, and Aspergillus flavus are regarded as the most important pathogenic agents. The aim of this research is to study the antifungal effects of Artemisia dracunculus L, Achillea wilhelmsii C. Koch, Bunium persicum, Cuminum cyminum L, Zataria multiflora Boiss, and Satureja hortensis extracts against Aspergillus Sp. The herbal extracts were prepared using maceration method. 50gr of ground plant was introduced into a 1-litre flask and macerated with 400ml of 70% ethanol for 24h and then was shaken on shaker. Afterwards, different concentrations of the extract were prepared in dimethyl sulfoxide solvent (DMSO). The extracts were filtered and sterilized. Suspension of each fungus was separately prepared with 1×106 CFU/ml concentration. The antifungal effects of the extracts were measured through NCCLS protocols and Broth dilution method. The control and comparison were done between the antifungal effects of the mentioned herbal extracts and Amphotericin B and Nystatin. The results indicated that the range of MIC and MFC values of these drugs was significantly higher (p≤0.05) compared to the prepared herbal extracts of different dilutions and control group of drug solvent, too. Results showed that the extracts of all herbal extracts have antifungal properties against Aspergillus sp.

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نویسنده نفر چندم مقاله نویسنده مسئول
احمد تاجه میریاولخير

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نام فایل تاریخ درج فایل اندازه فایل دانلود
07 2018-5-7-pp.53-57.pdf1397/06/111327957دانلود