| کد مقاله | 12456 |
| عنوان فارسی مقاله | |
| عنوان لاتین مقاله | Regulation of autophagy by polyphenols: Paving the road for treatment of neurodegeneration |
| نوع مقاله | مروری (Review) |
| بالاترین نمایه نامه بینالمللی | ISI |
| سطح مقاله | از مجلات برتر10%(scopus-Q1) |
| IF | 11.452 |
| عنوان نشریه | Biotechnology Advances |
| نوع نشریه | خارجی ایندکس شده |
| شماره نشریه | 6 |
| دوره | 36 |
| تاریخ انتشار شمسی | 1397/08/10 |
| تاریخ انتشار میلادی | |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | https://www.sciencedirect.com/science/article/pii/S0734975017301532?via%3Dihub |
| DOI | |
| آدرس علمی (Affiliation) نویسنده متقاضی | Department of Pharmacology, Faculty of Pharmacy, Kermanshah University of Medical Sciences, Kermanshah, Iran |
| In the present paper, we will discuss on the importance of autophagy in the central nervous system, and outline the relation between autophagic pathways and the pathogenesis of neurodegenerative disorders. The potential therapeutic benefits of naturally occurring phytochemicals as pharmacological modulators of autophagy will also be addressed. Our findings provide renewed insight on the molecular modes of protection by polyphenols, which is likely to be at least in part mediated not only by their potent antioxidant and anti-inflammatory effects, but also through modulation of autophagic processes to remove the aberrant protein aggregates. |
| نویسنده | نفر چندم مقاله | نویسنده مسئول |
|---|---|---|
| سمیرا شیرویی | چهارم | خير |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| 1-s2.0-S0734975017301532-main.pdf | 1397/05/27 | 719142 | دانلود |