| کد مقاله | 18715 |
| عنوان فارسی مقاله | |
| عنوان لاتین مقاله | Opinion: "High-dose immunosuppression to prevent death after paraquat self-poisoning"- under estimation of a significant effect with small mortality rate reduction |
| نوع مقاله | نامه به سردبیر (Letter to Editor, Author Reply ) |
| بالاترین نمایه نامه بینالمللی | pubmed |
| سطح مقاله | هیچکدام |
| IF | |
| عنوان نشریه | Current Rheumatology Reviews |
| نوع نشریه | خارجی ایندکس شده |
| شماره نشریه | |
| دوره | |
| تاریخ انتشار شمسی | 1402/03/15 |
| تاریخ انتشار میلادی | |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | https://pubmed.ncbi.nlm.nih.gov/36125830/ |
| DOI | 10.2174/1573397118666220823155018 |
| آدرس علمی (Affiliation) نویسنده متقاضی |
| A randomised double blinded clinical trial about high dose immunosuppression in Paraquat self-poisoning was published by Professor I. Gawaramanna et al. Before their research it seems that a little overestimation might be present in the small previous non randomised clinical trials. This new valuable work clarified the previous exaggerated favourable response to immunosuppression in paraquat self-poisoning, however their analysis underestimated the favourable response to high dose immunosuppression. According to their results, high dose immunosuppression could decrease mortality considering serum paraquat level and effect time of immunosuppressive drugs but the opposite is concluded. They did not mention to the impact of incomplete sample size on their results. Severe paraquat self-poisoning seems to be unresponsive to any treatment and these patients should be analyzed separately according to serum paraquat level. So after reanalysis of their results, the findings seem to be in favour of immunosuppression benefit in paraquat-self poisoning. |
| نویسنده | نفر چندم مقاله | نویسنده مسئول |
|---|---|---|
| بیتا انوری | اول | بلي |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| Opinion paraquat.jpg | 1401/11/28 | 298615 | دانلود |